I wish all these cultists would stop questioning authority.
and all these fascists!!!
Why don't they jab, mask, and vaxx passport like we force them to do.
bonus
IgG4 and cancer - a mechanism of action for cancer relapse and onset
Class switching and tumor promotion...
...
What this means, is that the unique ability of this typically rare subclass of antibody to switch out its arms, makes it unable to act out the things that I described above that IgG1 can do. Namely, form immune complexes and bind receptors on cells for removal of unwanted cells. So those three ways: the ADCC, ADCP and CDC - that aid in removal of unwanted cells are all nullified in the scenario where IgG4 is prevalent. Worse than that, since the subclass switch is literally the by-product of continuous antigen stimulation, then this is an immunological endorsement of a ‘win’ for IgG4 if we consider competition for binding sites. In effect, IgG4 outcompetes IgG1 and thus, the scales tip from tumor suppression, to tumor progression. All because of IgG4.
Now I don’t want to scare everyone, but persistent re-injection of a messenger RNA that encodes a foreign, highly immunogenic protein, is NOT a good idea in this context. This is precisely continuous antigen stimulation by the injectables’ contents and their by-products. Not only that, since we know that both the mRNA and the spike protein are long-lasting in the body, you mightn’t even have to re-inject yourself repeatedly to qualify as undergoing continuous antigen stimulation. In fact, I would bet that this would be a given. Furthermore, I would bet that due to this continuous antigen stimulation, the IgG1:IgG4 subclass ratio is inverted in people who are persistently making spike and/or re-injecting themselves, and that these people would be subject to cancer promotion, rather than suppression.
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