My only case of strep I ever fought, I didn't realize what it was for two days. And what a miserable-ass two days. I was in orlando on vacation, so god only knows where I caught it from. Ruined half of my trip until I loaded up on antibiotics / tylenol / salt water gargle / chloraseptic / halls / lots of sleep. Penicillin is the common antibiotic for strep, IIRC.
The peak of shittiness occured on the second night when my mouth would not stop producing saliva. In order to avoid drenching my pillow with drool, I had to hang my head off the edge of the bed over a cup to collect my spit. That ranks as one of the worst nights ever.