Sigh. People recommending a shotgun as "best" for home defense are ignorant. Also people making such stupid statements as you don't have to aim need to take their prized tacticool mossberg out to a range and see exactly the pattern size it will shoot. It's a lot smaller than you think, especially at a range of only 10 feet or closer. Thirdly, a small frail vegan liberal protein starved woman can't handle the recoil of a 12 gauge pump loaded with 3" 00 buck. Especially one with pistol grips.
A small semi-auto in 9MM is the correct choice in this example.