• Hosted by Branzone
  • PayPal Donate

A promising anti-ageing drug is about to undergo human trials for the first time

Submitted by: Odio @ 10:44 PM | Wednesday, June 22, 2016 | (url: http://www.scienc...)

Can we really hope to slow down the ageing process? The compound nicotinamide mononucleotide (NMN) has shown plenty of promise at increasing the lifespans of mice, and is about to be put to the test in human clinical trials for the first time.

Next month, 10 healthy volunteers will be given NMN to see if it can slow down ageing without any harmful side-effects. If the results are positive and the drug is given the all-clear for public use, it'll be the first genuine anti-ageing product on the market.

As George Dvorsky reports at Gizmodo, NMN stimulates the production of a class of proteins called sirtuins, which usually grow weaker as we get older.

When tested on mice, NMN was shown to stop the natural declines in metabolism, eyesight, and glucose intolerance, all of which tend to drop off as we get older. The question is, can it have the same effect in humans?

Mice are often used to test treatments because they share 95 to 98 percent of our genomes, and are afflicted by many of the same diseases. That said, there is plenty of doubt over how well tests on mice end up translating to the human body, so we'll just have to wait and see how well NMN does in human beings.

The trial will be run by Keio University in Japan with help from Washington University in St. Louis. The issue of ageing is of course a hot topic in Japan, where 40 percent of the population will be over 65 by the year 2055.

"We've confirmed a remarkable effect in the experiment using mice, but it's not clear yet how much [the compound] will affect humans," lead researcher Shin-ichiro Imai told The Japan News. "We'll carefully conduct the study, which I hope will result in important findings originating in Japan."

Category: Technology | 17 Comments
Tags: science

06-22-16 - 11:37 PM
Live long enough, you'd die from cancer anyway.

But what an awful idea. As if we (well, not "we", but browns, blacks and chinks) aren't insanely overpopulated as it is.
06-22-16 - 11:39 PM
Your vision is far too narrow my friend. Space is the future because brown people won't be able to afford to go.
06-23-16 - 12:55 AM
odio plz tell me wen dis is available... u are my goto go for drugs and drug accessories :sunny:
06-23-16 - 01:03 AM
proper hgh usage is the fountain of youth for men

literally
06-23-16 - 01:04 AM
MY PENIS IS FOUNTAIN OF YOUTH FOR HOT LADIES
06-23-16 - 06:00 AM
best anti-ageing drug

a Jaguar and a middle management expat position in Dubai

it makes you behave like a child again
06-23-16 - 06:20 AM
Originally posted by ArakAtak  
best anti-ageing drug

a Jaguar and a middle management expat position in Dubai

it makes you behave like a child again


Fucking sign me up.
06-23-16 - 05:15 PM
Originally posted by Odio  
Your vision is far too narrow my friend. Space is the future because brown people won't be able to afford to go.
Progressives will force it. We are literally doomed eventually.

Unless whites actually wake up and annihilate the rest.
06-23-16 - 05:16 PM
I look forward to voting my benefits longer while those under 40 strain to pay for my 80 year retirement.
06-23-16 - 05:52 PM
Unless it slows the effects aging has on the brain it doesn't matter much. :(
06-23-16 - 06:03 PM
Heeeeyooooo
06-23-16 - 06:10 PM
All wrong. The more oxygen you put in the air the longer we live. Couple that with protection from UV rays and we have 800-900 year potential.

Pills don't do anything, the Japanese have figured out how to reverse the effects of cancer using hyperbaric therapy and an adjustment in diet.

Of course you would only know these things if you taught Creation science in schools, but we have this situation today for a reason.
06-23-16 - 06:14 PM
Originally posted by Togowack  
All wrong. The more oxygen you put in the air the longer we live. Couple that with protection from UV rays and we have 800-900 year potential.

Pills don't do anything, the Japanese have figured out how to reverse the effects of cancer using hyperbaric therapy and an adjustment in diet.

Of course you would only know these things if you taught Creation science in schools, but we have this situation today for a reason.


are u fukin stupid

oxygen clearly toxic

[IMG]https://upload.wikimedia.org/wikipedia/commons/thumb/4/46/Symptoms_of_oxygen_toxicity.png/1280px-Symptoms_of_oxygen_toxicity.png[/IMG]
06-23-16 - 06:44 PM
Originally posted by Bughead  
Unless it slows the effects aging has on the brain it doesn't matter much. :(


Neural Stem Cells Could Let Us Replace Brain Cells and Restore Memory by Odio - TribalWar Forums
06-23-16 - 06:51 PM
I don't want to live forever.

I just want to live a really fucking long time and go out on my terms. Is that so much to ask?
Login to comment.