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Tailoring nanoparticle designs to target cancer based on tumor pathophysiology

Submitted by: Odio @ 12:47 PM | Sunday, February 21, 2016 | (url: http://www.pnas.o...)


Nanotechnology is a promising approach for improving cancer diagnosis and treatment with reduced side effects. A key question that has emerged is: What is the ideal nanoparticle size, shape, or surface chemistry for targeting tumors? Here, we show that tumor pathophysiology and volume can significantly impact nanoparticle targeting. This finding presents a paradigm shift in nanomedicine away from identifying and using a universal nanoparticle design for cancer detection and treatment. Rather, our results suggest that future clinicians will be capable of tailoring nanoparticle designs according to the patient's tumor characteristics. This concept of personalized nanomedicine was tested for detection of prostate tumors and was successfully demonstrated to improve nanoparticle targeting by over 50%.

Two invisibility cloak materials developed

Submitted by: elemeno @ 03:21 PM | Monday, August 11, 2008 | (url: http://www.telegr...)

In recent years, several teams around the world have shown with mathematics how a cloaking device could work in principle, by making light waves flow around an object - just as water in a river flows undisturbed around a smooth rock.

In principle, their invisibility cloak could be realised with artificial materials called "metamaterials," composite materials not found in nature, which could hide a person, or guide light around an ugly tower block which blocks a view.

Tiny nano science to test Russia's big hi-tech ambitions

Submitted by: Shadow(of)Death @ 12:30 AM | Sunday, June 15, 2008 | (url:

SAINT PETERSBURG (AFP) - In the world's largest country, tiny objects measured in billionths of a metre are the future of the economy -- or so the government claims.

Scientists across Russia are setting their minds to new inventions to net some of the billions of state dollars being poured into the field of nanotechnology. But they remain sceptical after years of neglect by the government.

Thermal cameras to detect breast cancer, sensors for spotting pipeline leaks and special coatings to prolong the life of industrial equipment were among the nano-devices on display at a business forum in Saint Petersburg this month.

[Orbitroll] Key to All Optical Illusions Discovered

Submitted by: Shadow(of)Death @ 09:51 AM | Monday, June 2, 2008 | (url:

Researcher Mark Changizi of Rensselaer Polytechnic Institute in New York says it starts with a neural lag that most everyone experiences while awake. When light hits your retina, about one-tenth of a second goes by before the brain translates the signal into a visual perception of the world.

Changizi now says it's our visual system that has evolved to compensate for neural delays, generating images of what will occur one-tenth of a second into the future. That foresight keeps our view of the world in the present. It gives you enough heads up to catch a fly ball (instead of getting socked in the face) and maneuver smoothly through a crowd. His research on this topic is detailed in the May/June issue of the journal Cognitive Science,

Japanese scientists create microscopic noodle bowl

Submitted by: Shadow(of)Death @ 11:36 PM | Thursday, May 29, 2008 | (url:

TOKYO - Japanese scientists say they have used cutting-edge technology to create a noodle bowl so small it can be seen only through a microscope.

The Japanese-style ramen bowl was carved out of microscopic nanotubes, Nakao said.

Carbon nanotubes are being explored for a wide range of uses in electronics and medicine because their structure endows them with powerful physical properties such as a strength greater than steel.

The ramen bowl experiment included a string of "noodles" that measured one-12,500th of an inch in length, with a thickness of one-1.25 millionth of an inch.

First Brain-controlled Video Gaming Headset Unveiled

Submitted by: Fox k @ 01:01 PM | Wednesday, February 20, 2008 | (url: http://www.tomsha...)

The company promises that players can more easily control certain actions and expressions and manipulating objects in the game using their brains instead of a keyboard or controller. In addition to these detections, the Emotiv EPOC comes with a gyroscope, which enables the camera or cursor to be controlled by head motions.

Nanogenerator Could Draw Energy from Human Blood

Submitted by: KnightMare @ 09:55 AM | Monday, July 23, 2007 | (url: http://news.softp...)

Scientists are working on a new type of nanogenerator that could draw the necessary energy from flowing blood in the human body, by using the beating heart and pulsating blood vessels. Once completed, this new cellular engine could find various applications, even beyond medicine.

Zhong Lin Wang and colleagues at the Georgia Institute of Technology hope to be able to incorporate the new nanogenerator into biosensors, environmental monitoring devices and even personal electronics that will
require no fuel source, internal or external.

Category: Technology | 10 Comments
Tags: nano nanotech