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Scientists Use Nanoparticles to Create a Universal Treatment for Allergies

Submitted by: Odio @ 10:28 PM | Saturday, January 7, 2017 | (url: https://futurism....)

ALLERGIES

Allergies are commonand depending on what you are allergic to and the severity of your allergies, it can be everything from a daily nuisance, to a debilitating handicap, to deadly.

Now, the promise of a universal treatment has just come to light. The method follows a system that could potentially end all allergies by using a Trojan horse concept that will allow our bodies to recognize common allergens as the harmless elements that they really are.

For years, scientists have tried in vain to prevent human immune systems from going haywire after being exposed to things such as pollen, animal fur, dust, etc. Their current efforts take a different approach. Instead of trying to calm the immune system, they are trying to use nanoparticles to carry these common allergens past the immune systems defenses so that it officially recognizes these elements as being harmless.

Category: Technology | 14 Comments
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Nanoparticle Treatment Eliminates Metastatic Cancer In Mice

Submitted by: Odio @ 05:40 AM | Tuesday, August 30, 2016 | (url: http://futurism.c...)

FINDING THE TARGET

In essence, cancer arises when a cells division mechanism breaks down and begins dividing uncontrollably, resulting in the development of tumors. When these out-of-control cells spread elsewhere, we have what is known as metastasis. which results in the development and spread of secondary tumors in the lungs, liver, and a host of other tissues.

These secondary tumors, also known as metastatic tumors, present the greatest risk and complications to cancer patients. Now new research may help provide an approach to eradicating the spread of these cancerous cells.

Led by Mauro Ferrari, a nanomedicine expert, a team of researchers has developed a method in which these spinoff tumors are tricked into consuming poison. The main component of this method is an agent called doxorubicin (dox), which has been used for years in cancer treatment, and the results in mice studies have shown this new method to be highly effective.

Dox eliminates cancer cells by jamming up DNA in the cell nucleus to prevent cell division. However, in the bloodstream, dox also negatively affects heart muscle cells and could lead to heart failure. To ensure that only tumor cells were killed, the researchers encapsulate the drug within a drug carrier.

For years, the team has been developing porous silicon particles for this purpose. With its small size and disklike shape, it is able to travel through normal blood vessels. Blood vessels near tumors are usually malformed and leaky ,which cause the particles to pool near the tumor. This allowed the drug agents to be delivered only to the tumor.

GETTING INTO THE SYSTEM

That wasnt the only problem researchers had to overcome. After delivering the agent, most tumor cells have membrane proteins which essentially act as tiny pumps that moves the drug outside the cell before it can have any effect. To counteract this defense system, the researchers linked the the dox molecules to stringlike polymer.

Category: Technology | 3 Comments
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Tailoring nanoparticle designs to target cancer based on tumor pathophysiology

Submitted by: Odio @ 12:47 PM | Sunday, February 21, 2016 | (url: http://www.pnas.o...)

Significance

Nanotechnology is a promising approach for improving cancer diagnosis and treatment with reduced side effects. A key question that has emerged is: What is the ideal nanoparticle size, shape, or surface chemistry for targeting tumors? Here, we show that tumor pathophysiology and volume can significantly impact nanoparticle targeting. This finding presents a paradigm shift in nanomedicine away from identifying and using a universal nanoparticle design for cancer detection and treatment. Rather, our results suggest that future clinicians will be capable of tailoring nanoparticle designs according to the patient's tumor characteristics. This concept of personalized nanomedicine was tested for detection of prostate tumors and was successfully demonstrated to improve nanoparticle targeting by over 50%.



Pentagon Looks to Breed Immortal Synthetic Organisms, Molecular Kill-Switch Included.

Submitted by: CrazyTexan @ 04:45 PM | Monday, February 8, 2010 | (url: http://www.switch...)

Apparently the department of defense wants to fund research on how to create loyal immortal "synthetic organisms." The organisms even come with a kill switch just in case.

Category: General | 28 Comments
Tags: orbital123